Technologies ＆ Solutions Double Tapered Shape/
Asymmetric Bevel^*
*Patented technology

Easy subcutaneous injection for everyone.
Terumo’s innovative ultra-thin pen needle shape that
redefines the conventional needle shape.

Terumo would particularly like to make daily injections less painful for children with diabetes. Injections are uncomfortable even for adults, and to minimize the risk of contact with pain receptors, the pen needle should be thinner. Thanks to its slim double tapered shape^*1, Terumo’s ultra-thin pen needle reduces the insulin injection force significantly^*2, which usually increases as the diameter of the needle becomes smaller. Using its advanced technology, Terumo has achieved the world’s top-class thin pen needle design.

^*1 Patented technology
^*2 Asakura T., Seino H., 2013, Jpn J Med Pharm Sci 69(1):137-146. & Asakura T., 2013, Jpn J Med Pharm Sci 69(1):147-155.

Both the inside and outside diameter becomes thinner toward the end so that
the force^1 applied to the needle is dispersed. Slim double tapered shape^2

The slim double tapered needle shape^*2 reduces the pain during stinging and bleeding,
while holding down the insulin injection force^*1, which usually increases as the diameter of the needle becomes smaller.
Thanks to the slim shape up to the base of the needle and the gentle taper angle,
the force applied to the needle is dispersed and the strength is more easily achieved.

^*1 Asakura T., Seino H., 2013, Jpn J Med Pharm Sci 69(1):137-146. & Asakura T., 2013, Jpn J Med Pharm Sci 69(1):147-155.
^*2 Patented technology

POINT01 Double tapered shape
— inside and outside

A double tapered shape in which both the outside and inside diameter become thinner toward the end is employed.
Although the needle tip is 34G, it provides less injection force^* than a conventional 32G pen needle.

^* Asakura T., Seino H., 2013, Jpn J Med Pharm Sci 69(1):137-146. & Asakura T., 2013, Jpn J Med Pharm Sci 69(1):147-155.

Conventional Needle Inside & outside straight Double Tapered Needle Inside & outside tapered

POINT02 Thin needle towards the base of the needle, but secures enough strength

The slim double tapered shape^*1 reduces the pain during stinging and bleeding, while holding down the insulin injection force significantly^*2, which usually increases as the diameter of the needle becomes smaller. Thanks to the slim shape up to the base of the needle and the gentle taper angle, the force applied to the needle is dispersed and the strength is more easily achieved.

^*1 Patented technology
^*2 Asakura T., Seino H., 2013, Jpn J Med Pharm Sci 69(1):137-146. & Asakura T., 2013, Jpn J Med Pharm Sci 69(1):147-155.

Double tapered shape achieved with Terumo’s advanced technology that
requires micron and submicron accuracy.

Minimizing risk of contact with pain receptors,
Terumo makes the diabetes self-treatment environment
easier to reduce burden on patients.

Asymmetric bevel^*

Conventionally, it has been said that the bevel surface of a pen needle should be “symmetrical and sharp”.
Terumo’s asymmetric bevel^* turned that theory on its head. Terumo’s engineers arrived at this double tapered shape by trying out various configurations of bevel. This shape requires the strictest accuracy during manufacturing, making it difficult to mass produce while ensuring precision. Terumo was able to manufacture this needle with fine precision in large quantities while maintaining its high quality by applying advanced production technology and stringent quality control.

^* Patented technology

POINT01 Cuts instead of puncturing

Terumo has developed an asymmetric bevel^*1 that cuts the skin instead of puncturing it. This effectively decreases penetration resistance^*2.

^*1 Patented technology
^*2 T. Asakura, 2013, JpnJ Med Pharm Sci 69(1):147-155

Combine Terumo’s advanced technologies with your business –
as subcutaneous administration for self-injection increases in popularity.

Terumo provides less painful self-treatments.

Terumo NANOPASS series
―Pen needle as a customer-oriented solution

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OurCare-interview-

Hisao Nishikawa

Development & Technology Section
(Life Care Solution)
Kofu East Factory
Medical Care Solutions Company

The driving force behind the development of the "less painful injection needle" was the desire of our engineers to help children cope with diabetes, after learning what they are going through.

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